Table 2.
Risk factors for splanchnic vein thrombosis: results of univariate analysis
| Splanchnic vein thrombosis | p Value | ||
| Yes (n = 38) | No (n = 213) | ||
| Age (y) | 49.2 (6.9) | 49.5 (8.8) | 0.86 |
| Sex (M/F) | 28/10 | 168/45 | 0.52 |
| Indication for transplantation | 9 (23.7%) | 50 (23.5 %) | 0.72 |
| Alcohol related cirrhosis | 6 (15.8 %) | 16 (7.5 %) | |
| HBV related cirrhosis | 6 (15.8 %) | 36 (16.9 %) | |
| HCV related cirrhosis | 11 (28.9 %) | 73 (34.3 %) | |
| HCC | 2 (5.3 %) | 20 (9.4%) | |
| Biliary (PBC and PSC) | 4 (10.5 %) | 18 (8.5 %) | |
| Other | |||
| Prothrombin time (% of normal) | 52.6 (17.8) | 58.7 (20.6) | 0.08 |
| Factor V (% of normal) | 54.5 (21.2) | 62.1 (25.7) | 0.09 |
| Bilirubin (μmol/l) | 54.6 (79.4) | 68.1 (71.6) | 0.29 |
| Albumin (g/l) | 33 (5.5) | 34.8 (7.9) | 0.20 |
| Creatinine (μmol/l) | 77.7 (19.5) | 88 (83.8) | 0.45 |
| Platelets count (109/l) | 77.4 (36.3) | 111.6 (69.2) | 0.001 |
| Episodes of encephalopathy | 12/38 (31.6%) | 49/213 (23%) | 0.18 |
| Chronic encephalopathy | 2/38 (5.3%) | 14/213 (6.6%) | 0.30 |
| Episodes of ascites | 30/38 (78.9%) | 126/213 (59.2%) | 0.009 |
| Refractory ascites | 15/38 (39.5%) | 55/213 (25.8%) | 0.11 |
| Spontaneous bacterial peritonitis | 6/38 (15.8%) | 33/213 (15.5%) | 0.96 |
| Child-Pugh score (A/B/C) | 4/21/13 | 61/83/69 | 0.04 |
| MELD score | 12.7 (5) | 11.5 (6.6) | 0.80 |
| Oesophageal varices | 0.22 | ||
| None/grade1/grade 2/grade 3 | 5/9/18/6 | 51/42/101/19 | |
| Variceal bleeding | 18/38 (47.4%) | 48/165 (29.1) | 0.001 |
| Endoscopic treatment | 0.07 | ||
| Sclerosis/ligation | 8/4 | 20/13 | |
| Abdominal surgery in the past | 13/38 (34.2%) | 56/213 (26.3%) | 0.32 |
HBV, hepatitis B virus; HCV, hepatitis C virus; HCC, hepatocellular carcinoma; PBC, primary biliary cirrhosis, PSC, primary sclerosing cholangitis.