Table 3.

 Adjusted relative risks (95% confidence interval) of symptomatic gall stone disease according to quintiles of energy adjusted intakes of glycaemic index among US men in the Health Professionals Follow up Study, 1986–1998

	Quintiles of glycaemic index
	1 (lowest)	2	3	4	5 (highest)	p for trend
Cases of GSD	359	319	356	388	388	–
Person years	90 354	92 143	91 537	92 142	91 522	–
Model 1: age adjusted	1.00	1.05 (0.90, 1.22)	1.16 (1.00, 1.34)	1.18 (1.02, 1.37)	1.26 (1.08, 1.46)	0.02
Model 2: multivariate	1.00	1.02 (0.88, 1.19)	1.11 (0.96, 1.29)	1.13 (0.97, 1.31)	1.16 (0.99, 1.35)	0.09
Model 3: multivariate	1.00	1.03 (0.88, 1.20)	1.12 (0.96, 1.30)	1.14 (0.98, 1.33)	1.18 (1.01, 1.39)	0.04
Model 4: multivariate	1.00	1.02 (0.88, 1.19)	1.12 (0.96, 1.30)	1.14 (0.97, 1.33)	1.17 (1.00, 1.38)	0.07

GSD, gall stone disease.

†Model 2, multivariate model included the following: age, body mass index, weight change during the past two years, physical activity, thiazide diuretics, non-steroid anti-inflammatory drugs, pack years of smoking, alcohol intake, caffeine intake, dietary fibre, protein intake, and total energy intake.

Model 3, model 2 with additional adjustment for saturated and trans fats.

Model 4, model 2 with additional adjustment for monounsaturated fat, polyunsaturated fat, saturated fat, and trans fat.