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PLP immunostaining brains of IGF1Roligo-ko mice and their littermate controls. Brains from IGF1Roligo-ko mice (panels B and D) and their littermate controls (panels A and C) at 4 weeks (panels A and B) or 25 weeks (panels C and D) of age were stained with PLP antibody. CTX = cerebral cortex, and CC = corpus callosum. The scale bar represents 200 μm.
