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. 2005 Jul;54(7):987–993. doi: 10.1136/gut.2004.057968

Figure 1.

Figure 1

 Titres of IgG against human serum albumin adducted with malondialdehyde (MDA-HSA) and arachidonic acid hydroperoxides (AAHP-HSA) or against oxidised cardiolipin (Ox-CL) in patients with non-alcoholic fatty liver disease (NAFLD) and in healthy controls. Sera were tested at a 1:50 dilution in microplate ELISA plates coated with different antigens and revealed with peroxidase linked goat antihuman IgG antiserum. Results are expressed as optical density (od) at 490 nm after subtracting the background reactivity of each serum. Boxes show values within 25th and 75th percentiles, horizontal bar represents the median, 80% of values are between the extremities of the vertical bars (10th–90th percentiles), and extreme values are represented by individual symbols. Values under the boxes represent the percentage of subjects with IgG titres above the cut off value, calculated on the 97.5th percentile of the control population. Statistical significance, NAFLD versus controls: MDA-HSA p<0.0001 (95% confidence interval (CI) −0.169 to −0.11); AAHP-HSA, p<0.0001 (95% CI −0.042 to −0.018); Ox-CL p<0.0001 (95% CI −0.059 to −0.020).