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Patient characteristics
| Mesalazine enema (n = 71) | Placebo enema (n = 56) | |
| Age (y) (median (range)) | 42 (18–76) | 47 (19–79) |
| Sex (male) (n (%)) | 44 (62%) | 32 (57%) |
| Smoking habits (n (%)) | ||
| Non-smoker | 36 (51%) | 27 (48%) |
| Ex-smoker | 27 (38%) | 19 (34%) |
| Current smoker | 8 (11%) | 10 (18%) |
| Duration of UC (y) (median (range)) | 4 (0–35) | 8 (0–39) |
| <1 y (n (%)) | 17 (24%) | 8 (14%) |
| 1–10 y (n (%)) | 37 (52%) | 28 (50%) |
| >10 y (n (%)) | 17 (24%) | 20 (36%) |
