Table 5.

 Local surgical treatment (duodenotomy with polypectomy and/or ampullectomy) for duodenal neoplastic lesions

Author	Treatment	Follow up	Patients	Outcome	Postoperative
Soravia52	Duodenotomy with polypectomy (1) or ampullectomy (4)	4–34 months &;(mean 18)	5 FAP	Recurrence in 4 patients. 1 patient died of cancer	1 transient duodenal fistula
Morpurgo44	Transduodenal ampullectomy (1) or polyp excision (1)	6–24 months &;(mean 19)	2 FAP	Recurrence in 1 patient	1 severe pancreatitis
Alarcon46	Local resection	8–33 months &;(mean 20.2)	5 FAP	Recurrence in 4 patients. 1 had progressive metastatic adenocarcinoma	NS
Heiskanen5	Duodenotomy	0.4–15.1 years &;(median 6.8)	15 FAP	No significant difference in Spigelman stage preoperative and at latest endoscopy	No postoperative complications
Penna56	Duodenotomy with polypectomy	5–36 months &;(mean 13.3)	12 FAP	Recurrence in 12 patients	NS
Penna57	Duodenotomy with polypectomy	36–72 months &;(mean 53)	6 FAP	Recurrence in 6 patients	1 cholecystectomy for cholecystitis, 2 duodenal fistulas
de Vos tot Nederveen58	Duodenotomy with ampullectomy	4–13 months &;(mean 11)	8 FAP	Recurrence in 6 patients	1 minor morbidity*
de Vos tot Nederveen58	Duodenotomy with polypectomy	5–103 months &;(mean 29)	22 FAP	Recurrence in 17 patients. 1 death from metastatic disease	1 minor morbidity*
Ruo59	Duodenotomy with ampullectomy	35 months	1 FAP	Gastric cancer arising from a polyp at 35 months	No postoperative complications
Farnell60	Transduodenal local excision	10 years	53 sporadic and FAP patients	Recurrence rate of 32% at 5 years and 43% at 10 years of follow up	3 pancreatitis, 3 leaks, 2 delayed gastric emptying, 2 ileus, 1 fluid overload

*That is, wound infection, atelectasis, or urinary tract infection.

NS, not stated; FAP, familial adenomatous polyposis.