Skip to main content
. 2005 Jul;54(7):1034–1043. doi: 10.1136/gut.2004.053843

Table 5.

 Local surgical treatment (duodenotomy with polypectomy and/or ampullectomy) for duodenal neoplastic lesions

Author Treatment Follow up Patients Outcome Postoperative
Soravia52 Duodenotomy with polypectomy (1) or ampullectomy (4) 4–34 months &;(mean 18) 5 FAP Recurrence in 4 patients. 1 patient died of cancer 1 transient duodenal fistula
Morpurgo44 Transduodenal ampullectomy (1) or polyp excision (1) 6–24 months &;(mean 19) 2 FAP Recurrence in 1 patient 1 severe pancreatitis
Alarcon46 Local resection 8–33 months &;(mean 20.2) 5 FAP Recurrence in 4 patients. 1 had progressive metastatic adenocarcinoma NS
Heiskanen5 Duodenotomy 0.4–15.1 years &;(median 6.8) 15 FAP No significant difference in Spigelman stage preoperative and at latest endoscopy No postoperative complications
Penna56 Duodenotomy with polypectomy 5–36 months &;(mean 13.3) 12 FAP Recurrence in 12 patients NS
Penna57 Duodenotomy with polypectomy 36–72 months &;(mean 53) 6 FAP Recurrence in 6 patients 1 cholecystectomy for cholecystitis, 2 duodenal fistulas
de Vos tot Nederveen58 Duodenotomy with ampullectomy 4–13 months &;(mean 11) 8 FAP Recurrence in 6 patients 1 minor morbidity*
de Vos tot Nederveen58 Duodenotomy with polypectomy 5–103 months &;(mean 29) 22 FAP Recurrence in 17 patients. 1 death from metastatic disease 1 minor morbidity*
Ruo59 Duodenotomy with ampullectomy 35 months 1 FAP Gastric cancer arising from a polyp at 35 months No postoperative complications
Farnell60 Transduodenal local excision 10 years 53 sporadic and FAP patients Recurrence rate of 32% at 5 years and 43% at 10 years of follow up 3 pancreatitis, 3 leaks, 2 delayed gastric emptying, 2 ileus, 1 fluid overload

*That is, wound infection, atelectasis, or urinary tract infection.

NS, not stated; FAP, familial adenomatous polyposis.