Table 4.
Parameters significantly associated with homeostasis model assessment for insulin resistance (HOMA IR) in univariate and multivariate analysis in patients infected with genotype 1
Univariate analysis | Multivariate analysis | ||||
Coefficient | p Value* | Coefficient | SE | p Value** | |
Age | 0.38 | <0.0001 | 0.203 | 0.012 | 0.04 |
Duration of disease† | 0.25 | 0.04 | 0.085 | 0.018 | 0.33 |
BMI | 0.41 | <0.0001 | 0.103 | 0.03 | 0.27 |
ALT | 0.25 | 0.008 | 0.122 | 0.003 | 0.24 |
Activity score | 0.39 | 0.002 | 0.024 | 0.225 | 0.8 |
Fibrosis score | 0.46 | 0.0001 | 0.069 | 0.181 | 0.47 |
% of steatosis | 0.56 | <0.0001 | 0.27 | 0.013 | 0.004 |
BMI, body mass index; ALT, alanine aminotransferase; HOMA, homeostasis model assessment.
*Spearman’s test; **multiple regression.
†In 62 patients with known risk factors. Taking disease duration into account did not change the results.