Table 1.
Association between chronic inflammation and cancer in the gastrointestinal tract
Gastrointestinal &;location | Type of inflammation | Type of cancer |
Oesophagus | Gastro-oesophageal reflux disease | Barrett’s cancer (adenocarcinoma of the distal oesophagus) |
Stomach | Chronic gastritis (autoimmune or H pylori) | Gastric adenocarcinoma, MALT lymphoma, GIST |
Pancreas | Chronic pancreatitis (familial, autoimmune, alcohol) | Pancreatic cancer |
Bile ducts | Primary sclerosing cholangitis | Cholangiocarcinoma |
Small bowel | Coeliac disease, Crohn’s disease | MALT lymphoma, small bowel adenocarcinoma |
Large bowel | Ulcerative colitis, Crohn’s colitis | Colorectal cancer |