Figure 6.
Loss of mitochondrial membrane integrity after bcl-2-short interfering RNA (siRNA) transfection. (A) Representative density plots of fluorescence detector FL1-H (green fluorescence, breakdown of ΔΨm) versus FL2-H (red fluorescence, intact ΔΨm), depicting all acquired events of untreated YAP C cells (left) or 120 hours after transfection with 100 nM bcl5 (right). (B) Means (SEM) of three independent experiments. All bcl-2 specific siRNAs caused a rapid decrease in ΔΨm (p<0.05) while no significant change was observed for mock transfected cells.