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Cotransfer of CD4+CD62L+ cells from cytosin-guanosin containing oligodeoxynucleotide (CpG-ODN) treated and untreated donor animals in SCID mice. Donor animals were treated with CpG-ODN (10 µg/day over five days) or left untreated and either CD4+CD62L+ cells from untreated or CpG-DNA treated donors or both were transferred to SCID recipients. In vivo proliferation of cells in mesenteric lymph nodes was detected by BrdU incorporation.
