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. 2005 Oct;54(10):1402–1407. doi: 10.1136/gut.2004.062034

Table 5.

 Psychological parameters before and after two weeks of treatment

Parameter Before melatonin treatment (absolute baseline score)* After melatonin treatment (decrease in score)
Melatonin Placebo Melatonin Placebo
Total anxiety score 9.55 (0.74) 7.75 (0.87) 0.80 (0.74) 1.35 (0.39)
Total depression score 5.55 (0.98) 3.90 (0.52) 0.75 (0.91) 1.05 (0.48)

All data are geometric mean (SEM).

No statistically significant differences between the melatonin and placebo groups for any of the absolute baseline scores or after two weeks of treatment.