Table 1.
Age (y) | C/T−13910 genotype | Lactase activity (U/g protein) | L/S ratio | Allele ratio (%) C/T−13910* |
0.8 | CT | 85 | 1.11 | 48/52 |
1.1 | CT | 113 | 1.02 | 52/48 |
4.0 | CT | 31 | 0.49 | 48/52 |
4.3 | CT | 53 | 0.48 | 42/58 |
4.7 | CT | 40 | 0.62 | 40/60 |
4.9 | CT | – | – | 42/59 |
5.1 | CT | 6 | 0.08 | 48/52† |
6.7 | CT | 22 | 0.28 | 18/82 |
7.6 | CT | – | – | 16/84 |
11.1 | CT | 29 | 0.54 | 13/87 |
14.9 | CT | 21 | 0.40 | 17/83 |
17.0 | CT | 29 | 0.62 | 24/76 |
1.1 | CC | – | – | 52/48 |
5.0 | CC | 24 | 0.28 | 51/49 |
22.8 | CC | 6 | 0.08 | 49/51 |
*Defined by assessing cSNP G/A+593 in exon 1 of the lactase LCT gene.
†Carrier of a CLD mutation (unpublished data).