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Major physiological actions of endogenously produced hydrogen sulphide (H2S). Activation of ATP sensitive K+ channels (KATP) is a common mechanism of H2S physiological effects, which induce vasorelaxation and neuronal hyperpolarisation in the cardiovascular system and nervous system, respectively. H2S can also promote glutamate medicated transmission via N-methyl-D-aspartate receptors which enhance neuronal long term potentiation.
