Figure 1.

 Microvascular dysfunction is associated with radiation enteritis induced intestinal strictures. (A) Wireless capsule endoscopic appearance of radiated non-stenotic ileum. (B) Abdominal radiograph demonstrating capsule retention. (C) Capsule endoscopic appearance of an ileal “web” following radiation therapy. (D) Acetylcholine (Ach) induced dilation of microvessels from radiation induced intestinal stricture and adjacent normal calibre intestine. (E) Reactive oxygen species (ROS) production from intestinal arterioles isolated from “web” and normal calibre bowel. (F) Histology of radiation induced stricture. (G) Endothelial staining with CD34 immunolocalisation in the radiation induced intestinal web, demonstrating preservation of the endothelial layer in stricture microvessels. Consent from the patient regarding the publication of this case report and the images was obtained.