Figure 2.

 Dose related effect of intracisternal corticotropin releasing factor (CRF) on hepatic surface perfusion (A) and portal pressure (B) in urethane anaesthetised rats. After a 20 minute basal measurement, CRF (0.1, 0.2, 0.6, 1, 2, or 4 nmol) or 0.9% saline vehicle was injected intracisternally. Hepatic surface perfusion and portal pressure were monitored thereafter for 120 minutes. For other details, see legend to fig 1 ▶. Each column represents the mean (SEM) per cent change in hepatic surface perfusion at 60 minutes after injection. *p<0.05, **p<0.01 compared with the vehicle injection group.