Figure 8.
Effect of intracisternal preadministration of the selective CRF2 receptor antagonist K41498 on intracisternal corticotropin releasing factor (CRF) induced alterations in hepatic surface perfusion (A) and portal venous pressure (B) in urethane anaesthetised rats. K41498 (2 nmol) was intracisternally injected five minutes before intracisternal injection of CRF (2 nmol). For other details, see legend to fig 1 ▶. Each point represents the mean (SEM). *p<0.05, **p<0.01 compared with the vehicle treated group.