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. 2005 Feb;54(2):193–200. doi: 10.1136/gut.2004.046292

Figure 4.

Figure 4

 Effects of apple polyphenol extracts (APE) on total antioxidant intracellular activity and on lipid peroxidation in MKN 28 cells. (A) APE prevented xanthine-xanthine oxidase (X-XO) induced decrease in total antioxidant intracellular activity in MKN 28 cells. Cells were treated with serum free medium (control) or APE (10−4 M) for three hours and then with serum free medium or X (1 mM)-XO (50 mU/ml) for two hours. Mean (SD) of three separate experiments run in duplicate. *p<0.05 versus control; †p<0.05 versus X-XO. (B) APE prevented X-XO induced increase in cellular MDA in MKN 28 cells. Cells were treated with serum free medium (control) or APE (10−4 M) for three hours and then with serum free medium or X (1 mM)-XO (50 mU/ml) for two hours. Mean (SD) from three separate experiments run in duplicate. *p<0.05 versus control; †p<0.05 versus X-XO.