Figure 7.

 Nitric oxide (NO) concentrations in the mucosal and muscular layers of the rat stomach as a function of the concentration of administered nitrite. The experimental conditions were similar to those described in fig 6 ▶ except for the various concentrations (0–2 mM) of sodium nitrite administered. The majority of NO was detected in the superficial mucosal layers from each resected site, with little NO in the inner muscular layers. NO concentrations dose dependently increased as a function of the concentrations of nitrite administered in the mucosal layer of the gastro-oesophageal (GO) junction as well as in that of the distal stomach, although the former was consistently higher than the latter. Values are means (SD) of five rats. **Significantly different from respective control (p<0.01).