Figure 8.

 Concentrations of reduced glutathione in gastric tissue resected from the gastro-oesophageal (GO) junction and distal stomach. Sodium nitrite (2 mM) or water as a control was continuously injected over a period of four hours with bolus administration of 0.5 ml ascorbic acid solutiom (pH 2.0) every 30 minutes. Thereafter, tissue was obtained from the same parts of the stomach as in the DETC experiment. Reduced glutathione concentration was decreased by nitrite administration at the GO junction while it remained unchanged at the distal stomach. Mean values of five rats are represented by the horizontal bars. **p<0.01; NS, not significant.