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Concentration-response curves for the effects evoked by the protease activated receptor 4 (PAR4) activating peptides, GYPGKF-NH2 and AYPGKF-NH2, and the inactive control peptide, YAPGKF-NH2, on the longitudinal muscle of rat colon. The contractile effects are expressed as a percentage of the contraction to carbachol (CCh 10 μM). Each value is the mean (SEM) of 4–8 experiments.
