0—No significant abnormality |
Congestion, oedema, very occasional intravillous neutrophils, occasional apoptosis, hyperplastic lymphoid follicles. |
1—Mild |
Superficial mucosal erosion, patchy mucosal haemorrhage, prominent germinal centres with apoptosis and intrafollicular haemorrhage, focal, acute inflammatory infiltrate within the lamina propria, cryptitis, and crypt abscesses. |
2—Moderate |
Mucosal ulceration, mucosal/submucosal haemorrhage, intact muscularis propria. |
3—Severe (localised) |
Mucosal ulceration, focal transmural haemorrhage involving muscularis propria and serosa. |
4—Severe (generalised) |
Mucosal ulceration and diffuse transmural haemorrhage involving muscularis propria and serosa. |