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. 2004 Feb;53(2):207–213. doi: 10.1136/gut.2003.024521

Table 1.

Definition of intestinal injury grading

Grade Histological findings
0—No significant abnormality Congestion, oedema, very occasional intravillous neutrophils, occasional apoptosis, hyperplastic lymphoid follicles.
1—Mild Superficial mucosal erosion, patchy mucosal haemorrhage, prominent germinal centres with apoptosis and intrafollicular haemorrhage, focal, acute inflammatory infiltrate within the lamina propria, cryptitis, and crypt abscesses.
2—Moderate Mucosal ulceration, mucosal/submucosal haemorrhage, intact muscularis propria.
3—Severe (localised) Mucosal ulceration, focal transmural haemorrhage involving muscularis propria and serosa.
4—Severe (generalised) Mucosal ulceration and diffuse transmural haemorrhage involving muscularis propria and serosa.