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. Author manuscript; available in PMC: 2007 Jan 18.
Published in final edited form as: J Biomater Sci Polym Ed. 2006;17(10):1141–1158. doi: 10.1163/156856206778530731

Figure 1.

Figure 1

Phase-contrast photomicrographs of various morphologies exhibited by populations of IC-21 macrophages on polymer surfaces at early (<50% confluent) culture times. Cells exhibit primarily astral morphology with some filopodial extensions (E, bold arrow) at sub-confluent culture conditions on TCPS (A, E). However, as these cultures progress to 100% confluence cells adopt a typical ‘cobblestone-like’ pattern of cell growth with fewer extensions (data not shown). On PS (B, F) cells exhibit membrane ruffling (F, arrows) and filopodia, similar to (but to a lesser extent than) behavior observed on Teflon® AF. Morphology is more compact on PLA surfaces (C, G), in contrast to the lengthy filopodia and large areas of membrane ruffling (D and H, arrows) observed on Teflon® AF. Results are representative of numerous (>3) fields and (>3) trials.