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Comparative effects of 1α,25-dihydroxyvitamin D3 (1α,25D3) on Interleukin (IL)-1-stimulated prostaglandin E2 production by rheumatoid synovial fibroblasts and human articular chondrocyte in vivo
| Fibroblasts | Chondrocytes | |
| Control | 1 | 1 |
| + 1α,25D3 | 1.23 ± 0.16 | 1.35 ± 0.25 |
| + IL-1 | 7.07 ± 1.09 | 3.7 ± 1.05 |
| + IL-1 + 1α,25D3 | 1.61 ± 0.7 | 4.23 ± 1.10 |
Data given are normalized relative to control values and are expressed ± SEM for three cultures of each cell type.
