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Immunocytochemistry of cultured rheumatoid arthritis fibroblasts using monoclonal antibodies against human CENP-E protein [10,11]. Note the strong expression of CENP-E protein rheumatoid fibroblasts (a) in comparison with the absence of CENP-E protein in osteoarthritis fibroblasts (b). (c) The positive control was performed with antifibroblast antibodies. Immunogold-silver staining, original magnifications × 800 (a, b) and × 1000 (c).
