Abstract
To study the effect of thyrotoxicosis on growth, 46 children and adolescents presenting with thyrotoxicosis have been reviewed and followed up for several years, in most cases until adult height was achieved. At presentation the children were underweight for height but were above expected heights even if already well advanced in puberty. Despite bone ages often being very advanced at diagnosis, the condition had no adverse effect on ultimate stature, which was commonly greater than that expected on the basis of parental height. Wight was rapidly regained on treatment, but nevertheless the younger subjects continued to be underweight despite adequate prolonged control of thyrotoxicosis.
Full text
PDFSelected References
These references are in PubMed. This may not be the complete list of references from this article.
- Barnes H. V., Blizzard R. M. Antithyroid drug therapy for toxic diffuse goiter (Graves disease): thirty years experience in children and adolescents. J Pediatr. 1977 Aug;91(2):313–320. doi: 10.1016/s0022-3476(77)80843-3. [DOI] [PubMed] [Google Scholar]
- Buckler J. M. Skeletal age changes in puberty. Arch Dis Child. 1984 Feb;59(2):115–119. doi: 10.1136/adc.59.2.115. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Johnsonbaugh R. E., Bryan R. N., Hierlwimmer R., Georges L. P. Premature craniosynostosis: A common complication of juvenile thyrotoxicosis. J Pediatr. 1978 Aug;93(2):188–191. doi: 10.1016/s0022-3476(78)80493-4. [DOI] [PubMed] [Google Scholar]
- Park R. W., Frasier S. D. Hyperthyroidism under 2 years of age. Am J Dis Child. 1970 Aug;120(2):157–159. doi: 10.1001/archpedi.1970.02100070101015. [DOI] [PubMed] [Google Scholar]
- ROOT A. W., BONGIOVANNI A. M., HARVIE F. H., EBERLEIN W. R. TREATMENT OF JUVENILE THYROTOXICOSIS. J Pediatr. 1963 Sep;63:402–407. doi: 10.1016/s0022-3476(63)80427-8. [DOI] [PubMed] [Google Scholar]
- Robinson D. C., Hall R., Munro D. S. Grave'S's disease, an unusual complication: raised intracranial pressure due to premature fusion of skull sutures. Arch Dis Child. 1969 Apr;44(234):252–257. doi: 10.1136/adc.44.234.252. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Tanner J. M., Whitehouse R. H., Takaishi M. Standards from birth to maturity for height, weight, height velocity, and weight velocity: British children, 1965. I. Arch Dis Child. 1966 Oct;41(219):454–471. doi: 10.1136/adc.41.219.454. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Von Harnack G. A., Tanner J. M., Whitehouse R. H., Rodriguez C. A. Catch-up in height and skeletal maturity in children on long-term treatment for hypothyroidism. Z Kinderheilkd. 1972;112(1):1–17. doi: 10.1007/BF00491961. [DOI] [PubMed] [Google Scholar]