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. 2006 Sep 15;3(4):A121.

Table 3.

Alcohol-attributable Fractions (AAFs)a and Mean Age at Death in Canada, 2002

Chronic Disease Categories AAF (%) Aged 69 and Younger Mean Age at Death, y

Men Women Men (n = 89,022) Women (n = 35,599)
Detrimental effectsb
 Malignant neoplasms (3.4%) 15.8 4.0 57.3 55.7
   Mouth and oropharynx cancer 20.5 8.4 56.9 56.4
   Esophageal cancer 19.2 7.1 56.9 57.2
   Liver cancer 16.1 7.6 56.9 59.1
   Laryngeal cancer 19.3 15.4 59.1 59.1
   Breast cancer 0 3.3 0 54.5
   Other cancers 3.2 1.0 54.3 53.8
 Neuropsychiatric conditions (49.9%) 57.4 35.5 52.1 52.3
   Alcoholic psychoses 100 100 51.8 54.4
   Alcohol abuse 100 100 53.0 49.9
   Alcohol dependence syndrome 100 100 54.7 54.9
   Unipolar major depression 1.1 0.1 48.0 54.7
   Degenerative nervous system due to alcohol 100 100 59.1 52.0
   Epilepsy 39.4 18.7 41.2 46.7
   Alcoholic polyneuropathy 100 100 NA NA
 Cardiovascular diseases (33.7%) 2.5 0.3 54.8 56.5
   Hypertensive disease 6.4 0.6 56.4 59.7
   Alcoholic cardiomyopathy 100 100 52.7 56.4
   Cardiac arrhythmias 7.0 1.4 53.7 54.6
   Cerebrovascular disease 0.7 NA 56.2 NA
     Hemorrhagic stroke 1.4 NA 59.1 NA
    Esophageal varices 34.2 17.9 57.5 59.6
 Digestive diseases (13.0%) 38.7 55.5 50.3 54.6
   Alcoholic gastritis 100 100 58.3 64.5
   Cirrhosis of the liver 41.3 26.4 55.6 54.5
   Acute and chronic pancreatitis 13.5 3.4 54.4 56.4
   Chronic pancreatitis, alcohol induced 55.6 66.7 50.0 52.0
   Cholelithiasis -16.2 -8.6 49.8 42.8
Average mean age at death for detrimental effects 55.2 54.7
Beneficial effectsb
 Type 2 diabetes mellitus -5.1 -2.5 56.9 57.7
 Ischemic heart disease -3.1 -0.6 57.4 58.6
 Cerebrovascular disease NA -0.7 NA 56.1
   Ischemic stroke -0.2 -2.9 56.8 53.5
   Hemorrhagic stroke NA -0.2 NA 59.6
 Cholelithiasis -3.3 -0.8 58.9 54.3
Average mean age at death for beneficial effects 57.4 57.7
Average mean age at death for net effects 53.8 53.4

NA indicates not applicable.

a

AAF refers to the number of alcohol-related deaths divided by the overall number of deaths

b

Numbers were derived by multiplying AAFs with number of diagnoses and result in numbers with decimals; there may be rounding errors. A negative number indicates that more deaths were prevented than caused by alcohol for the respective disease condition.