Table 2.
List of all the Gene Ontology significant terms with more than two annotated genes on the array (N > 2)
| GO category number | GO term | P value | n/N | Genes |
| 6412 | Protein biosynthesis | <0.001 | 15/205 | EIF4G1(↑), ITGB4BP(↑), LAMR1(↑), RPL7(↑), RPL9(↑), RPL10(↑), RPL12(↑), RPL23A(↑), RPS5(↑), RPS10(↑), RPS20(↑), RPL14(↑), NOLA2(↑), RPL10A(↑), RPL38(↑) |
| 50930 | Induction of positive chemotaxis | 0.002 | 2/4 | AZU1(↓), IL8(↑) |
| 6878 | Copper ion homeostasis | 0.002 | 2/4 | ATOX1(↑), MT2A(↑) |
| 6337 | Nucleosome disassembly | 0.002 | 2/4 | HMGA1(↑), SUPT16H(↑) |
| 6508 | Proteolysis and peptidolysis | 0.002 | 13/290 | ANPEP(↑), AZU1(↓), CAPN2(↑), NEDD8(↑), PLAT(↑), PLAU, PRSS1(↓), ADAM15(↑), NPEPPS(↑), KLK11(↓), SUPT16H(↑), CASP14(↓), KLK12(↓) |
| 7266 | Rho protein signal transduction | 0.004 | 3/18 | RHOA(↑), ARHGDIB(↑), CFL1(↑) |
| 1516 | Prostaglandin biosynthesis | 0.008 | 2/8 | MIF(↑), PTGDS(↓) |
| 30036 | Actin cytoskeleton organization and biogenesis | 0.010 | 4/47 | RHOA(↑), ARHGDIB(↑), CFL1(↑), PFN1(↑) |
| 42157 | Lipoprotein metabolism | 0.011 | 2/9 | APOA1(↓), HMGA1(↑) |
| 6928 | Cell motility | 0.012 | 6/104 | ACTN4(↑), CTGF(↑), IL8(↑), SPOCK(↑), ACTR3(↑), ARPC2(↑) |
| 43065 | Positive regulation of apoptosis | 0.013 | 2/10 | BCL2L11(↓), MTCH1(↑) |
| 6445 | Regulation of translation | 0.014 | 3/28 | MKNK2(↑), LAMR1(↑), PPP2CA(↑) |
| 43066 | Negative regulation of apoptosis | 0.016 | 2/11 | MIF(↑), ANGPTL4(↑) |
| 30155 | Regulation of cell adhesion | 0.019 | 2/12 | IL8(↑), PPP2CA(↑) |
| 6979 | Response to oxidative stress | 0.024 | 3/34 | ATOX1(↑), DUSP1(↑), GPX2(↓) |
| 7596 | Blood coagulation | 0.026 | 4/61 | GP9(↓), PLAT(↑), PLAU(↑), THBD(↑) |
| 6869 | Lipid transport | 0.026 | 3/35 | APOA1(↓), HMGA1(↑), LBP(↓) |
| 9611 | Response to wounding | 0.030 | 2/15 | CTGF(↑), MDK(↑) |
| 6355 | Regulation of transcription, DNA-dependent | 0.037 | 11/1,042 | BTF3L3(↑), RUNX2(↓), ENO1(↓), GATA6(↓), HMGA1(↓), FOXA2(↓), NFKB2(↓), SSRP1(↑), UBE2V1(↑), NFAT5(↓), SIX4(↓) |
| 45941 | Positive regulation of transcription | 0.047 | 2/19 | GATA6(↓), HMGA1(↑) |
| 7243 | Protein kinase cascade | 0.047 | 3/44 | MKNK2(↑), STK17A(↓), MAP4K1(↓) |
| 7605 | Perception of sound | 0.048 | 4/74 | GJA1(↑), PMP22(↑), WDR1(↑), TIMM8B(↑) |
P values were determined by Fisher's exact test. Genes is a list of differentially expressed genes annotated to the GO terms; upward and downward arrows indicate up- and down-regulation, respectively. GO, gene ontology; n, number of differentially expressed genes annotated to the GO term; N, number of genes represented on the array annotated to the GO term;