Table 5.
Self-reported health conditions and risk of rheumatoid arthritis, Denmark 1998 to 2003
| Women | Men | Both genders | |||
| Number of patients/controls | ORa (95% CI) | Number of patients/controls | ORa (95% CI) | ORa (95% CI) | |
| Mononucleosis | 12/24 | 0.74 (0.35 to 1.56) | 3/12 | 0.48 (0.13 to 1.84) | 0.63 (0.33 to 1.20)b |
| Hay feverc | 61/63 | 1.32 (0.89 to 1.97) | 14/36 | 0.56 (0.27 to 1.17) | 1.13 (0.81 to 1.58) |
| Atopic dermatitis | 19/24 | 0.99 (0.51 to 1.90) | 7/10 | 1.46 (0.51 to 4.20) | 1.12 (0.65 to 1.94) |
| Asthmac,d | 24/40 | 0.74 (0.43 to 1.28) | 4/28 | 0.22 (0.07 to 0.67) | 0.58 (0.36 to 0.93)e |
| Stomach or duodenal ulcer | 20/32 | 0.70 (0.38 to 1.27) | 12/30 | 0.70 (0.33 to 1.47) | 0.73 (0.47 to 1.16)b |
| Diarrhea | 49/84 | 0.72 (0.48 to 1.07) | 27/53 | 1.01 (0.58 to 1.75) | 0.81 (0.59 to 1.12) |
| Type I diabetesc | 2/1 | 2.84 (0.22 to 36.05) | 3/6 | 1.15 (0.26 to 5.00) | 1.30 (0.39 to 4.34) |
| Thyroid diseasec | 38/34 | 1.45 (0.87 to 2.40) | 3/2 | 2.32 (0.35 to 15.44) | 1.52 (0.94 to 2.46)b |
| Periodontal disease | 83/118 | 0.95 (0.67 to 1.33) | 41/88 | 0.92 (0.57 to 1.47) | 0.91 (0.70 to 1.19) |
| Urinary tract infection | 171/256 | 0.76 (0.57 to 1.01) | 13/40 | 0.57 (0.28 to 1.14) | 0.73 (0.57 to 0.95)e |
| Cancer | 12/19 | 0.70 (0.33 to 1.49) | 4/2 | 5.51 (0.89 to 34.19) | 1.01 (0.51 to 1.99) |
| Blood transfusion | 51/66 | 0.99 (0.65 to 1.51) | 12/26 | 0.84 (0.39 to 1.79) | 0.98 (0.68 to 1.40) |
| Tonsillectomy, adenoidectomy, appendectomy, or splenectomy | 163/214 | 0.97 (0.73 to 1.29) | 63/124 | 1.00 (0.65 to 1.55) | 0.98 (0.78 to 1.24) |
| Schizophrenia among first-degree relatives | 6/5 | 2.19 (0.62 to 7.77) | 6/6 | 1.77 (0.51 to 6.11) | 2.08 (0.88 to 4.93)b |
Numbers of patients and controls refer to participants who ever had the health condition in question. aORs represent comparisons between 'ever' versus 'never' (= reference) for each presented disease, with adjustment for birth year, year or pseudo-year of RA diagnosis, and (when combined) gender. bTest for homogeneity 0.05 < p < 0.20. cPhysician-verified diagnosis. dAsthma before age 45 years. eTest for homogeneity p < 0.05. CI, confidence interval; OR, odds ratio.