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. 2006 Jun 28;8(4):R100. doi: 10.1186/ar1985

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Copyright © 2006 Fujikado et al.; licensee BioMed Central Ltd.

This is an open access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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Arthritis-related gene clusters on chromosome (Chr.) 11. The peak at the Chr. 11, 81- to 83-megabase (Mb) (#4–6) includes Ccl and Slfn family clusters. An expanded view of this region in 2-Mb window is shown. Hierarchical clustering patterns of the expression levels are shown below. Ccl and Slfn genes are clearly clustered in specific narrow loci and augmented in arthritis. CC, Cysteine-Cysteine type; KS, interleukin-1 receptor antagonist-knockout mice; TS, human T-cell leukemia virus type I- transgenic mice; WT, wild-type mice.