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. 2006 Jun 28;8(4):R100. doi: 10.1186/ar1985

Table 1.

Identified arthritis-related gene clusters by transcriptome mapping

ID Chr. Position (Mb) n of genes * n of total genes Included gene families
1 17 33 10 48 MHC class II
2 17 34 8 67 Complement
3 17 35 2 40 MHC class I

17 33–35 20 155 MHC class II/Complement/MHC class I

4 11 81 3 10 CC chemokine ligand
5 11 82 5 25 Schlafen
6 11 83 3 23 CC chemokine ligand

11 81–83 11 58 Schlafen/CC chemokine ligand

7 6 68 3 19 Immunoglobulin kappa chain
8 6 69 4 16 Immunoglobulin kappa chain
9 6 70 2 13 Immunoglobulin kappa chain

6 68–70 9 48 Immunoglobulin kappa chain

10 12 112 4 8 Immunoglobulin heavy chain
11 12 113 2 3 Immunoglobulin heavy chain

12 112–113 6 11 Immunoglobulin heavy chain

12 6 124 5 23 Complement/C-type lectin superfamily
13 15 79 5 27 Colony stimulating factor 2 receptor, beta
14 19 11 5 32 Membrane spanning four-domain, subfamily A
15 2 165 4 32 -
16 3 146 4 10 Guanylate nucleotide binding protein
17 17 17 4 11 Formyl peptide receptor
18 19 5 4 45 -
19 1 75 3 15 -
20 1 167 3 16 Selectin
21 1 174 3 20 (Fc receptor)
22 2 91 3 26 -
23 2 129 3 18 -
24 4 131 3 18 -
25 5 136 3 38 -
26 7 3 3 28 Paired-Ig-like receptor
27 7 37 3 46 -
28 7 39 3 29 Serum amyloid A
29 7 120 3 30 -
30 9 126 3 15 CC chemokine receptor
31 11 70 3 30 -
32 11 102 3 37 -
33 11 114 3 33 -
34 11 117 3 23 -
35 15 105 3 25 -
36 19 12 3 33 -
37 X 63 3 40 -

*Numbers of total genes in the corresponding 1 megabase were obtained from a Mouse Genome Search in The Bioinformatics Analytical Toolkit [20]. CC, Cysteine-Cysteine type; Chr., chromosome; Fc, Fragment crystallizable; ID, identification number; Ig, immunoglobulin; Mb, megabase; MHC, major histocompatibility complex.