Table 2.
MHC2TA -168A>G genotype and clinical characteristics of Austrian rheumatoid arthritis patients
| AA genotype | AG genotype | GG genotype | P value | ||
| Dominant, AA:AG + GG genotypes | Recessive, AA + AG:GG genotypes | ||||
| Rheumatoid factor (n (%)) | 0.23 | 0.27 | |||
| Positive | 136 | 107 | 14 | ||
| Negative | 42 | 42 | 8 | ||
| Anti-cyclic-citrullinated peptide (n (%)) | 0.89 | 0.38 | |||
| Positive | 61 | 57 | 7 | ||
| Negative | 32 | 29 | 6 | ||
| Stage (n (%)) | 0.15 | 0.40 | |||
| 1 | 37 | 40 | 7 | ||
| >1 | 138 | 107 | 15 | ||
| Age at onset of rheumatoid arthritis (years ± SD) | 50 ± 16 | 50 ± 16 | 52 ± 12 | 0.90 | 0.50 |
SD, standard deviation. Data for rheumatoid factor were available from 349 patients, data for the clinical stage of the disease from 344 patients and data for the anti-cyclic-citrullinated peptide were available from 192 patients. The stage of disease is defined by the radiologic stage (Steinbroker).