Table 2.

Major interleukin-10 (IL-10)-induced transcripts in monocytes from patients with rheumatoid arthritis

Symbol	Encoded protein	Gene name	IL-10-induced changes (folds)
			Patient 1	Patient 2
BMPR1A	Bone morphogenetic protein receptor, type IA	ALK-3	2.41	2.37
BMPR1B	Bone morphogenetic protein receptor, type IB	ALK-6	0.74	9.79
BMPR2	Bone morphogenetic protein receptor, type II	BMPR-II	1.81	1.32
CCL15	Chemokine (C-C motif) ligand 15	MIP-1 delta/MIP-5	1.84	1.07
CCR5	Chemokine (C-C motif) receptor 5	CCR5	1.93	1.11
CXCL3	Chemokine (C-X-C motif) ligand 3	GRO3	2.17	0.83
IRAK2	Interleukin-1 receptor-associated kinase 2	IRAK2	1.93	2.73
SOCS3	Suppressor of cytokine signaling 3	SSI-3	3.84	15.29
TGFBR2	Transforming growth factor, β receptor II	TGFBR2	2.17	0.79
TGFBR3	Transforming growth factor, β receptor III	TGFBR3	2.04	0.29
TIMP1	Tissue inhibitor of metalloproteinase 1	TIMP1	3.49	1.46
TLR2	Homo sapiens Toll-like receptor 2	TLR2	1.38	2.28
TLR3	Homo sapiens Toll-like receptor 3	TLR3	3.03	16.61
TLR4	Homo sapiens Toll-like receptor 4	TLR4	2.66	1.86
TLR9	Homo sapiens Toll-like receptor 9	TLR9	2.44	0.78
TLR10	Homo sapiens Toll-like receptor 10	TLR10	2.78	0.90
TNFRSF1B	Tumour necrosis factor receptor superfamily, member 1B	TNFR2/p75	2.64	0.91
TNFRSF7	Tumour necrosis factor receptor superfamily, member 7	CD27	8.99	0.57
TNFRSF8	Tumour necrosis factor receptor superfamily, member 8	CD30	3.13	1.15
TNFSF11	Tumour necrosis factor (ligand) superfamily, member 11	TRANCE	3.50	2.01
TNFRSF11A	Tumour necrosis factor receptor superfamily, member 11a, activator of nuclear factor-κB	Rank	2.50	0.56
TNFSF4	Tumour necrosis factor (ligand) superfamily, member 4	OX40L	2.67	1.06
TRAF4	TNF receptor-associated factor 4	TRAF4	2.18	1.00
TRAF6	TNF receptor-associated factor 6	TRAF6	3.49	0.56
PUC18	PUC18 plasmid DNA	pUC18	0.00	0.00
ACTB	β-actin	β-actin	0.92	0.91