Table 5.

Zonal distribution of proteoglycan

	Normalized PG in superficial zonea			Normalized PG in mid zoneb			Normalized PG in deep zonec
Rabbit no.	Control	Loaded	Difference	Control	Loaded	Difference	Control	Loaded	Difference
1	0.14	0.20	0.06	0.06	0.29	0.23	0.03	0.11	0.08
2	0.05	0.01	-0.04	0.09	0.06	-0.02	0.06	0.09	0.03
3	0.27	0.33	0.06	0.22	0.31	0.09	0.19	0.28	0.09
4	0.27	0.18	-0.08	0.13	0.19	0.05	0.07	0.14	0.07
5	0.18	0.17	-0.01	0.17	0.16	-0.01	0.14	0.18	0.04
6	0.06	0.17	0.11	0.15	0.15	0.00	0.18	0.22	0.04
Mean	0.16	0.18	0.02	0.14	0.20	0.06	0.11	0.17	0.06
SD	0.09	0.10	0.07	0.06	0.09	0.10	0.07	0.07	0.03
Significanced			>0.05			>0.05			0.003

^aSuperficial zone of cartilage is from 0 to 8 μm; ^bmid zone is from 8 to 53 μm; ^cdeep zone is from 53 to 100 μm; the zone thicknesses were determined by polarized light microscopy; ^dsignificance was calculated using the two-tailed, paired Student t test (α = 0.05). PG, proteoglycan; SD, standard deviation.