Table 2.
Effect of the “minimum effective dose” of LPS on development of preimplantation stage embryos collected from superovulated pregnant animals. Data is expressed as mean ± 1SEM, with all values given in (%) of abnormal embryos. Means bearing similar superscripted alphabets do not differ from each other at P ≤ .05 (based on Duncan's multiple range test). ANOVA: treatment (T), F-value = 959.694 (P < .001), df 1, 24; days of pregnancy (P), F-value = 251.514 (P < .001), df 3,24; T × P interaction F-value = 195.104 (P < .001), df 3,24.
| Days of pregnancy | No of animals used | Control animals | LPS-treated animals | ||||||
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| Total no of embryos recovered | No of abnormal embryos recovered | Loss in yield (%) | Abnormal embryos (%) | Total no of embryos recovered | No of abnormal embryos recovered | Loss in yield (%) | Abnormal embryos (%) | ||
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| 1.5 | 4 | 116 ± 5 | 0 ± 5 | 0 | 2 ± 1.199(e) | 116 ± 5 | 0 ± 6 | 0 | 3 ± 1.472(e) |
| 2.5 | 4 | 116 ± 5 | 12 ± 5 | 0 | 9 ± 1.914(d) | 116 ± 5 | 48 ± 5 | 0 | 42 ± 1.658(b) |
| 3.5 | 4 | 116 ± 5 | 16 ± 5 | 0 | 13 ± 2.179(d) | 116 ± 5 | 56 ± 6 | 0 | 48 ± 2.041(b) |
| 4.375 | 4 | 104 ± 5 | 8 ± 4 | 10 | 8 ± 2.027(c) | 72 ± 5 | 64 ± 4 | 38 | 92 ± 5.566(a) |