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The effects of deletion or disruption of genes relating IGF-II bioavailability on growth of the placenta and fetus and on the fetal to placental weight ratio in mice in late gestation
| Gene | Placental weight | Fetal weight | F:P weight ratio |
|---|---|---|---|
| Igf2 | 75% | 60% | 85% |
| Placental specific Igf2P0 | 65% | 75% | 115–130% |
| Igf-2R | 140% | 140% | 100% |
| H19 | 140% | 130% | 90% |
| Igf-2R and H19 | 230% | 200% | 80% |
The data show knockout percentage wild-type. Data from Efstratiadis (1998); Chiao et al. (2002); Constancia et al. (2005).
