Table 1.
Fibre cross-sectional area (μm2) | Fibre cross-sectional area expressing a particular MHC isoform (μm2) | |||||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Condition | Leg | I | I/IIA | IIA | IIA/IID(X) | IIA/IID(X)/IIB | IID(X) | IID(X)/IIB | IIB | I/IIA/IID(X)/IIB | I | IIA | IID(X) | IIB |
IRR | Control | 818 ± 45 | 635 ± 191 | 975 ± 55 | 479 ± 228 | — | 1335 ± 71 | 255 ± 255 | 2593 ± 130 | — | 854 ± 57 | 976 ± 56 | 1334 ± 71 | 2591 ± 129 |
Sham | 1037 ± 123a | 604 ± 244 | 1154 ± 151 | 550 ± 265 | 231 ± 231 | 1507 ± 152 | 717 ± 340 | 2971 ± 221 | — | 1019 ± 122 | 1152 ± 148 | 1498 ± 150 | 2938 ± 220 | |
IRR- | Control | 996 ± 89 | 247 ± 168 | 1009 ± 85 | — | — | 1287 ± 114 | — | 2564 ± 174 | — | 979 ± 91 | 1002 ± 86 | 1287 ± 114 | 2564 ± 174 |
Stim | Stim | 1018 ± 40a | 952 ± 227b | 988 ± 78 | 592 ± 222 | 1563 ± 129d | 930 ± 276d | 204 ± 204 | 966 ± 345a,b,d | 1113 ± 416 | 1104 ± 73a | 1310 ± 73a,b | 1217 ± 277 | 1277 ± 347a,b,d |
Stim | Control | 685 ± 34 | 218 ± 112 | 688 ± 31a | — | — | 963 ± 43 | 201 ± 201 | 1771 ± 74a | — | 680 ± 33 | 687 ± 31a | 971 ± 46 | 1770 ± 74a |
Stim | 893 ± 47b | 558 ± 125 | 919 ± 79b,d | 584 ± 176 | 1262 ± 121d | 369 ± 183a,b,c,d | — | 652 ± 166a,b,d | 578 ± 287 | 889 ± 47b,c | 1064 ± 92b,c | 974 ± 171d | 922 ± 202a,b,d |
Data are means ± s.e.m. expressed as muscle fibre areas.
Different from IRR-control
different from contralateral control
different from IRR-Stim
different from IRR (P < 0.05).