Table 2.
Distribution of shut times for channels activated by glutamate, AMPA, KA and SYM 2081
| τ1 (ms) area (%) | τ2 (ms) area (%) | τ3 (ms) area (%) | τ4 (ms) area (%) | |
|---|---|---|---|---|
| Glutamate | ||||
| 200 nm | 0.34 ± 0.08 | 7.0 ± 0.7 | 30.2 ± 2 | 182 ± 4 |
| (8 ± 1) | (44 ± 3) | (10 ± 1) | (38 ± 2) | |
| 10 μm | 0.18 ± 0.01 | 8.5 ± 0.9 | 37.5 ± 2.2 | — |
| (14 ± 2) | (72 ± 5) | (14 ± 3) | ||
| 20 mm | 0.14 ± 0.01 | 2.7 ± 0.2 | 28.6 ± 4.9 | 345 ± 50 |
| (34 ± 2) | (34 ± 3) | (19 ± 2) | (13 ± 1) | |
| AMPA | ||||
| 1 μm | 0.22 ± 0.02 | 9.2 ± 0.3 | 93 ± 13 | — |
| (19 ± 4) | (46 ± 2) | (35 ± 2) | ||
| 10 μm | 0.16 ± 0.07 | 8.5 ± 0.3 | 55.7 ± 7.5 | — |
| (23 ± 1) | (67 ± 1) | (10 ± 1) | ||
| KA (30 μm) | — | 4.6 ± 1.3 | — | — |
| SYM 2081 (100 μm) | 0.13 ± 0.02 | 9.5 ± 1.3 | 133 ± 11 | — |
| (7 ± 2) | (57 ± 9) | (37 ± 7) | ||