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. 2006 Mar 31;573(Pt 2):453–468. doi: 10.1113/jphysiol.2006.107375

Figure 5. A-type K+ current density is significantly higher in male and OVX females compared with females.

Figure 5

A-type currents were isolated in colonic myocytes by application of TEA (10 mm) to the bathing solution. Typical A-type currents recorded from male, non-pregnant female and OVX female mice are shown in A–C, respectively. Statistical analysis revealed that the density of A-type currents was significantly higher for males compared with non-pregnant females (D). A-type currents were also of significantly greater density for the OVX group compared with non-pregnant females (E). There was no difference in A-type current density between male and OVX mice (F). Voltage dependence of activation and inactivation were shifted to slightly more negative potentials for both male and OVX mice (G and H).