Figure 7. Effects of 1 mm orthovanadate on IKs in myocytes pretreated with TK inhibitors.
A, C and E, examples of reversible stimulation of IKs by orthovanadate (Van). B, D and F, Summaries of the effects of TK inhibitor pretreatment (left) and subsequent cotreatment with orthovanadate (right) on the amplitude (% control) of the IKs tail; ††P < 0.001 versus before application of orthovanadate. Number of myocytes is shown in parentheses. A23, tyrphostin A23; A25, tyrphostin A25; GST, genistein; Van, orthovanadate.