Figure 4. Effect of src-PTK activation on Kv1.3 current in freshly isolated human T lymphocytes.

Kv1.3 currents were elicited with 900 ms long depolarizing pulses to +50 mV (−80 mV HP) every 30 s either in the present (n = 5) or absence (control, n = 5) of the src activator peptide EPQYEEIPIYL (1 mm) in the patch pipette. The peak current amplitude values (normalized for the maximum current observed after establishing a whole cell configuration) were plotted against time from the time point of maximum current recording (set as 0). *P < 0.05