Table 1.
Demographics
CN without lacunes |
CN with lacunes |
|||
---|---|---|---|---|
Non-HTN | HTN | Non-HTN | HTN | |
N (F/M) | 27 (17/0) | 3 (1/2) | 8 (4/4) | 4 (1/3) |
Age (years)* | 71.9 ± 7.6 | 74.3 ± 6.5 | 76.7 ± 4.8 | 78.2 ± 6.2 |
Interval (years) | 3.6 ± 0.9 | 2.7 ± 1.0 | 3.5 ± 1.2 | 3.0 ± 0.6 |
APOE ɛ4 | 6 | 0 | 5 | 1 |
MMSE | 29.4 ± 0.8 | 30.0 ± 0.0 | 29.0 ± 0.9 | 28.5 ± 1.7 |
ΔMMSE (per year) | 0.02 ± 0.22 | 0.14 ± 0.25 | 0.02 ± 1.0 | −0.4 ± 0.5 |
DLR | 10.6 ± 1.4 | 10.5 ± 2.2 | 10.0 ± 1.7 | 9.7 ± 1.5 |
ΔDLR (per year) | −0.08 ± 0.79 | −0.21 ± 0.31 | 0.11 ± 0.90 | −0.52 ± 1.18 |
WMH (cm3)* | 7.4 ± 10.5 | 2.5 ± 1.9 | 5.9 ± 2.6 | 17.7 ± 8.8 |
HTN: hypertension, MMSE: mini-mental state examination, DLR: delayed list recall. Twelve words need to be remembered in the DLR test, ΔMMSE: (first MMSE score – second MMSE score)/scan interval, ΔDLR: (first DLR score – second DLR score)/scan interval.
p < 0.05, t-test, between subjects with and without lacunes.