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Dose-dependant inhibition of PrPSc formation in N2a/22L cells by Mabs. (A) Densitometric measurements of PrPSc bands detected in the Western blots fitted to sigmoidal dose–response curves. Values are given as mean ± SD from at least three independent experiments. (B) Western blots of PK-treated cell lysates from N2a/22L cells treated for 4 days with different concentrations of Mabs.
