Table 1.

Characterization of anti-PrP Mabs

Antibody	Antigen localization†	KD
7D9	Unknown, nonlinear	8.2 ± 0.19 × 10−10M
8B4	35–45	2.4 ± 0.60 × 10−10M
6D11	93–109	8.5 ± 0.18 × 10−11M
11G5	115–130 (1st β-strand)	5.4 ± 0.17 × 10−10M
7H6	130–140	2.2 ± 0.04 × 10−10M
7A12	143–155 (α-helix A)	1.9 ± 0.05 × 10−10M
2C2	153–165 (2nd β-strand)	3.4 ± 0.15 × 10−9M
8H4	175–185 (α-helix B)	3.8 ± 0.11 × 10−10M
9H7	143–231	10.3 ± 0.43 × 10−10M
8F9	220–231	10.6 ± 0.50 × 10−9M

^†Numbers correspond to residues of murine PrP. K_D values are given as mean ± SD from at least three independent experiments.