TABLE 3.

Examples: the calculation of protein intrinsic isothermal compressibility from experimental compressibility

	α-Lactalbumin	Lysozyme	Myoglobin
	12.4	7.73	11.2
(δV2)*	11.8	10.2	—
(%)	18	16	20
(%)	29	38	30
(%)	53	46	50
	−0.46	−0.71	−1.8
2.43	−1.12	−1.72	−4.37
†	13.5	9.5	17.5

^* is protein intrinsic compressibility calculated from volume fluctuations (44) for α-lactalbumin and lysozyme.

^† is the intrinsic compressibility calculated from experimental data including the hydration contribution.