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. Author manuscript; available in PMC: 2007 Jan 23.
Published in final edited form as: J Pharmacol Exp Ther. 2004 Dec 1;312(3):1314–1320. doi: 10.1124/jpet.104.078741

Fig. 1.

Fig. 1

Percentage of [35S]GTPγS stimulation by increasing concentrations of (+)BW373U86 or DPDPE pretreated with either vehicle (sterile water) or 10 nM NTI compared with basal [35S]GTPγS binding in the caudate putamen of coronal brain slices from naive rats. EC50values were approximately 1.1 nM, 0.92 μM, 0.49 μM, and undetermined for vehicle NTI with (+)BW373U86 (•), 10 nM NTI with (+)BW373U86 (○), vehicle NTI with DPDPE (▪), and 10 nM NTI with DPDPE (□), respectively.