. Author manuscript; available in PMC: 2007 Dec 1.

Published in final edited form as: Neuropsychopharmacology. 2006 May 3;31(12):2580–2590. doi: 10.1038/sj.npp.1301085

Table 1.

Mean (±SEM) Thermal (Minimum Core Body Temp, °C), Behavioral (% Time Spent Immobile), and Cardiovascular (Minimum Heart Rate = HR, b.p.m.) Changes During Swim Stress

Treatment	Min. core temp	% Immobile	Min. HR
Vehicle (nonsink)	24.9 (0.3)	74 (2)	247 (14)
Vehicle (sink)	24.8 (0.4)	67 (1.7)^#	142 (13)^***
Average vehicle	24.8 (0.2)	70.8 (1.8)	193 (26)
3.2 mg/kg methylatropine	24.8 (0.2)	82 (6.2)^*	235 (11)
32 mg/kg antalarmin	25.6 (0.3)	76 (2.3)	135 (18)^*
3.2 methylatropine+32 antalarmin	23.8 (0.3)^*	85 (1.9)^***	240 (3)
30 mg/kg R121919	ND	80 (2.6)^*	ND
0.1 mg/kg astressin B	24.8 (0.5)	77 (2)	229 (11)
20 mg/kg RU486	24.4 (0.2)	75 (3.2)	243 (6)

p<0.05,

^***

p<0.001 (vs average vehicle) N = 6–9 rats/treatment.

p<0.05 (vs vehicle nonsink), ND = not determined.

Bold values represent measurements significantly changed versus vehicle-treated rats.