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. 2006 Nov;169(5):1505–1522. doi: 10.2353/ajpath.2006.051090

Table 1.

Definitions of the Metabolic Syndrome

Risk factors National Cholesterol Education Program’s Adult Treatment Panel III (ATP III) (≥3 of 5 criteria necessary) World Health Organization (WHO) 1999 (impaired glucose regulation or hyperinsulinemia and ≥2 of criteria necessary) European Group on Insulin Resistance (EGIR) 2002 (hyperinsulinemia and ≥2 of criteria necessary)
Impaired glucose regulation 110 to 126 mg/dl (6.1 to 7.0 mmol/L) Plasma glucose: fasting ≥6.1 mmol/L or 2-hour postglucose load ≥7.8 mmol/L or capillary whole blood glucose: fasting ≥5.6 mmol/L or 2-hour postglucose load ≥7.8 mmol/L Fasting plasma ≥6.1 mmol/L or capillary whole blood ≥5.6 mmol/L
Hyperinsulinemia Not included Fasting serum insulin ≥ third quartile for control group Fasting serum insulin ≥ third quartile for nondiabetic control group
Abdominal obesity Men: waist circumference ≥40 inches (102 cm); women: waist circumference ≥35 inches (89 cm) Waist-to-hip ratio >0.85 or BMI >30 kg/m2 Waist circumference >80 cm
Triglycerides ≥150 mg/dl (1.7 mmol/L) Fasting serum triglyceride ≥1.7 mmol/L Fasting serum triglyceride >2.0 mmol/L and/or HDLc <1.0 mmol/L and/or treatment for dyslipidemia
HDLc Men: ≤40 mg/dl (1.04 mmol/L); women: ≤50 mg/dl (1.3 mmol/L) Not included Included with triglycerides
Hypertension ≥130/≥80 mm Hg ≥140/90 mm Hg Systolic blood pressure ≥140 mm Hg and/or diastolic blood pressure ≥90 mm Hg and/or treatment for hypertension
Microalbuminuria Not included Albumin/creatinine ratio ≥30 mg/g Not included