Table 1.
Definitions of the Metabolic Syndrome
Risk factors | National Cholesterol Education Program’s Adult Treatment Panel III (ATP III) (≥3 of 5 criteria necessary) | World Health Organization (WHO) 1999 (impaired glucose regulation or hyperinsulinemia and ≥2 of criteria necessary) | European Group on Insulin Resistance (EGIR) 2002 (hyperinsulinemia and ≥2 of criteria necessary) |
---|---|---|---|
Impaired glucose regulation | 110 to 126 mg/dl (6.1 to 7.0 mmol/L) | Plasma glucose: fasting ≥6.1 mmol/L or 2-hour postglucose load ≥7.8 mmol/L or capillary whole blood glucose: fasting ≥5.6 mmol/L or 2-hour postglucose load ≥7.8 mmol/L | Fasting plasma ≥6.1 mmol/L or capillary whole blood ≥5.6 mmol/L |
Hyperinsulinemia | Not included | Fasting serum insulin ≥ third quartile for control group | Fasting serum insulin ≥ third quartile for nondiabetic control group |
Abdominal obesity | Men: waist circumference ≥40 inches (102 cm); women: waist circumference ≥35 inches (89 cm) | Waist-to-hip ratio >0.85 or BMI >30 kg/m2 | Waist circumference >80 cm |
Triglycerides | ≥150 mg/dl (1.7 mmol/L) | Fasting serum triglyceride ≥1.7 mmol/L | Fasting serum triglyceride >2.0 mmol/L and/or HDLc <1.0 mmol/L and/or treatment for dyslipidemia |
HDLc | Men: ≤40 mg/dl (1.04 mmol/L); women: ≤50 mg/dl (1.3 mmol/L) | Not included | Included with triglycerides |
Hypertension | ≥130/≥80 mm Hg | ≥140/90 mm Hg | Systolic blood pressure ≥140 mm Hg and/or diastolic blood pressure ≥90 mm Hg and/or treatment for hypertension |
Microalbuminuria | Not included | Albumin/creatinine ratio ≥30 mg/g | Not included |