Table 4A.

Continued

Bird et al, 199825	Schoen et al, 199922
BMI Q4 (29.2 to 51.0 kg/m2) versus Q1 (15.9 to 24.41 kg/m2): polyp risk M and F 1.6 (1.1, 2.2)*; Weight gain over last 10 years Q4 (>2.3 to 33.3 kg) versus Q1 (−21.8 to −0.7 kg): polyp risk M and F 1.7 (1.1, 2.9)*; Adult weight gain Q4 (>22.7 to 81.8 kg) versus Q1 (−34.1 to 4.5 kg): polyp risk M and F 1.4 (0.9, 2.1); BMI Q4 (29.2 to 51.0 kg/m2) versus Q1 (15.9 to 24.41 kg/m2): large polyp risk M and F 2.5 (1.1, 5.4)*	Fasting serum glucose Q4 (111 to 657 mg/dl) versus Q1 (53 to 96 mg/dl): M and F 1.8 (1.0, 3.1)*; 2-hour serum glucose Q4 (171 to 691 mg/dl) versus Q1 (38 to 110 mg/dl): M and F 2.4 (1.2, 4.7)*; 2-hour serum insulin Q4 (102 to 500 IU/ml) versus Q1 (5 to 45 IU/ml): M and F 2.0 (1.0, 3.8)*; Waist/hip ratio Q4 (0.961 to 2.33) versus Q1 (0.61 to 0.93): M and F 2.6 (1.4, 4.8); LDL Q4 (≥336.8 mg/dl) versus Q1 (24.8 to 109.8 mg/dl): M and F 0.5 (0.3, 0.9)*; Waist circumference Q4 (101.2 to 167 cm) versus Q1 (32.5 to 91 cm): M and F 2.2 (1.2, 4.1)
American men and women, cases = 483, controls n = 483; case control study	American men and women, n = 5849; prospective population-based cohort study
Sex; age; date of sigmoidoscopy; smoking; race; regular use of NSAID; vigorous leisure time; exercise >3 times/week; caloric intake; dietary fiber	Age; sex; physical activity
50 to 75 years old; cases: diagnosed for the first time with histologically confirmed adenomatous polyps; controls: no adenomas or polyps
Invasive cancer; inflammatory bowel disease; familial polyposis; previous bowel surgery
BMI 5 years before; BMI 10 years before; BMI at age 18 years; height; net weight gain over the last 5 years; number of large weight changes (≥4.5 kg); number of rapid large weight changes (≥4.5 kg in ≤5 years)	BMI; HDL; TG; glucose intolerance; diabetes; fasting insulin