Table 2.
Association of autoantibodies with shared epitope (SE) alleles
| SE/x | SE/SE | *0401/*0101 | |
| All patients | |||
| RF | 1.8 | 3.7* | 8.7* |
| AFA | 2.2* | 5.1* | 9.5* |
| Anti-Sa | 2.0 | 7.1* | 18.9* |
| Anti-CCP | 2.0 | 5.0* | 10.9* |
| AKA | 1.4 | 3.1* | 3.4* |
| RA patients | |||
| RF | 1.8 | 2.7 | 5.3 |
| AFA | 2.2 | 4.9* | 6.5* |
| Anti-SA | 1.9 | 4.0* | 10.6* |
| Anti-CCP | 2.0 | 3.0 | 7.2* |
| AKA | 1.4 | 2.9 | 3.3 |
Numbers represent odds ratios for having each autoantibody associated with shared epitope alleles. SE/x, SE/SE, DRB *0401/*0101 were each compared with patients with no shared epitope alleles. *P<0.05 by Chi-square after Bonferroni adjustment for multiple comparison, RF, Rheumatoid factor; AFA, antifilaggrin antibody; CCP, cyclic citrullinated peptide; AKA, antikeratin antibody.