Table I. Dissection of the domains of SUP-12.
Domain | Residues | Rescue | Localization | RNA-binding | Solubility |
---|---|---|---|---|---|
Full-length | 1–248 | Yes | Nuclei | ND | I nsoluble |
RRM | 1–117 | No | Nuclei cytoplasm | Yes | Soluble |
A/Q-rich | 118–248 | No | Nuclei cytoplasm | ND | Insoluble |